International Journal of Research and Review

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Original Research Article

Year: 2018 | Month: June | Volume: 5 | Issue: 6 | Pages: 88-93

Evaluation of Costus Igneus on Lipid Profile Status and Anti- Hyperglycemic Activity in Alloxan Induced Diabetic Rats

Leena Chimurkar1, Ranjana Kale2, Sushilkumar Varma3

1Assist. Prof., 2Professor, 3Prof & Head,
Dept.of Pharmacology, MGIMS, Sewagram Wardha.

Corresponding Author: Leena Chimurkar


The present study was made to investigate an anti-hyperglycemic effect of Costus igneus in alloxan induced diabetic mellitus. Diabetes was induced by alloxan (150mg/kg i.p) into rats. Crude extract of leaves of Costus igneus was used in alloxan induced diabetic rats. Glibenclamide used as a standard antidiabetic drug in one group to compare the effect with test drug. Blood glucose level was estimated and pancreas was send to study histopathology in rats. All groups show significant results after giving costus igneus. It has been concluded that the leaves of costus igneus having good hypoglycemic activity.

Key words: Costus igneus, Alloxan, Glebeclamide, Diabetes mellitus, anti-hyperglycemic effect

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