Original Research Article
Year: 2022 | Month: September | Volume: 9 | Issue: 9 | Pages: 316-320
DOI: https://doi.org/10.52403/ijrr.20220934
To Study the Prevalence and Severity of Anemia in Solid Malignancy Patients
Uthaya Sankar M.K1, Raja M2, Damodaran Kumaran P3
1Professor and Unit Chief of Medicine, Department of General Medicine, Sri Manakula Vinayagar Medical College and Hospital, Puducherry 605107
2Postgraduate residents, Department of General Medicine, Sri Manakula Vinayagar Medical College and Hospital, Puducherry 605107
3Assistant Professor of Oncology, Department of General Medicine, Sri Manakula Vinayagar Medical College and Hospital, Puducherry 605107
Corresponding Author: Raja M
ABSTRACT
Background: Anemia in solid malignancy may be due to tumor-associated bleeding, hemolysis, hypersplenism, reduced production of EPO, nutritional deficiencies, bone marrow failure and toxicity associated with therapies which increases the mortality.
Aim: To study the prevalence and severity of anemia in solid malignancy patients.
Methods: Hospital based -cross sectional study done on patients above 18 years with solid malignancy with elevated C-reactive protein level (CRP). Sample size was 50.Complete blood count, peripheral smear and CRP were measured.
Results: Among 50 patients, the overall prevalence of anemia in solid malignancy with elevated CRP was 100%. The mean hemoglobin was lower in female patients 8.2 ± 1.40 g/dl (mean±SD) compared with male patients 8.4 ± 2.01g/dl (mean±SD). 62% patients were having elevated CRP value ranges from 0.6mg/dl to 1 mg/dl with a mean hemoglobin of 8.3 ± 1.32 (mean±SD) and 38% were having CRP of more than 1mg/dl with a mean hemoglobin of 8.1 ± 1.02 (mean±SD). Among the different types of malignancy, colorectal and gynecological tract group were found to have low mean hemoglobin value of 7.8 ± 1.04 (mean±SD) and 7.9 ± 1.13 (mean±SD).Most of them were having moderate anemia (70%) and normocytic normochromic anemia (78%).
Conclusion: The overall prevalence of anemia in solid malignancy patients with elevated inflammatory marker like CRP was 100%. Most of them were having moderate anemia (70%), normocytic normochromic type (78%).
Keywords: Anemia, Solid malignancy, Hemoglobin.
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