Review Paper
Year: 2022 | Month: July | Volume: 9 | Issue: 7 | Pages: 713-723
DOI: https://doi.org/10.52403/ijrr.20220775
Analyzing Hereditary 5-HT Abnormalities in Obsessive-Compulsive Disorder (OCD)
Phantira Suppathavevut1, Preedaporn Pholphuet2
1,2Triamudomsuksa, Pathumwan, Bangkok, Thailand 10330
Corresponding Author: Phantira Suppathavevu
ABSTRACT
Serotonin (5-HT) is one of the most essential and complicated neurotransmitters in humans, being an underlying cause of several neuropsychiatric disorders. Obsessive-Compulsive Disorder (OCD) is one of the disorders that is proved to be strongly correlated with 5-HT. This review focuses on how genetics of 5-HT influences the manifestation of OCD and suggests that further study needs to be done in order to find the genuine genetic cause of the disease and approach better treatments in the future. Smaller units, such as single nucleotide polymorphism (SNP), can bring an enormous change to the expression of gene and unveil the paradox of the findings from the past decades. Therefore, the unexplainable variety of findings might be answered if it is studied more thoroughly and utilizes new advanced technology.
Keywords: Behavioral and social sciences; Neuroscience; Obsessive-Compulsive Disorder; Serotonin; Polymorphism
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