IJRR

International Journal of Research and Review

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Review Article

Year: 2022 | Month: May | Volume: 9 | Issue: 5 | Pages: 15-22

DOI: https://doi.org/10.52403/ijrr.20220504

A Review on Development of Fast Dissolving Tablet and Approaches in Pharmaceutical Dosage of Atorvastatin

Dr. Rajesh Asija1, Karishma Sharma2, Seema Yadav Trimukhe3

1,2,3Maharishi Arvind Institute of Pharmacy, Jaipur-302020, Rajasthan, India.

Corresponding Author: Karishma Sharma

ABSTRACT

Dosage form tablets and capsules in the current era still have gained considerable importance and acceptance by the formulation scientists, physicians, and the patients due to their numerous advantages which include easy self-administration and cost-effectiveness experienced by the patients. However, the drug delivery through the tablet dosage is no doubt, associated with potential drawbacks which include difficulty for the older and pediatric patients to swallow (dysphagia), low fraction of drug available for absorption in the bloodstream due to first-pass hepatic effect, and a slower therapeutic outcome in patients. Fast dissolving tablets have been emerged as a newer concept, in novel drug delivery systems that offer not only an alternative to conventional tablet dosage form, but also provide better therapeutic outcome, the ultimate solution, and a better option for the problem faced by the patients of such age group and diseases.

Keywords: Pharmaceutical dosage form, fast dissolving tablet, atorvastatin.

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