IJRR

International Journal of Research and Review

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Research Paper

Year: 2022 | Month: December | Volume: 9 | Issue: 12 | Pages: 192-197

DOI: https://doi.org/10.52403/ijrr.20221221

Dano Active AD Oil Flummox Drug Resistance Instinct in Certain Strains of Pityrosporum Ovale

Aruna V1, Amruthavalli GV1, Sumithira Rajakumar2, Gayathri Rajagopal1

1Dr. JRK’s Research and Pharmaceuticals Pvt. Ltd, No.18 & 19, Perumal Koil Street, Kunrathur, Chennai- 69
2ST.Anne's Arts and Science College, Grand Northern Trunk Rd, Kanakan Chatram, Madhavaram, Chennai-110

Corresponding Author: Aruna V

ABSTRACT

The present study describes the new rulebook in dealing dandruff where targeting the resistant isolates of Pityrosporum ovale and also preventing / delaying the process of the strains acquiring such defense mechanism.  We have established a total herbal formulation, a Siddha cosmetic oil preparation having the dual effect in neutralizing the drug resistant strains causing dandruff as well as hindering the process of drug resistance or such adaptation in the strain.  The entry of an array of antidandruff preparations just for the commercial endpoint only had made the lazy, commensal, lipophilic and highly fastidious yeast like fungi – Pityrosporum ovale to become resistant or adapt to deal various non-drug antidandruff agents like Zinc pyrithione, Climbazole, Octopirox etc.  We have established how the herbal armamentarium in Dano active AD oil could achieve the above benefit through a well-designed scientific experiment and details are presented in the article.

Keywords: Dandruff, AD oil, Dano, P.ovale, drug resistance, anti-fungal

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