Research Paper
Year: 2021 | Month: March | Volume: 8 | Issue: 3 | Pages: 205-211
Formulation of Gel Peel Off Catechins Mask from Gambir (Uncaria Gambir (Hunter) Roxb) with the PVP K-30 Concentration Variation
Henni Rosaini1, Indra Makmur1, Etika Ayu Lestari1, Wahyu Margi Sidoretno2, Rina Desni Yetti1
1Departement of Pharmaceutics School Science (STIFARM) Padang, West Sumatera 25147, Indonesia
2Departement of Pharmaceutical and Food Analyses, Faculty of Medicine and Health Science, Abdurrab University, Indonesia
Corresponding Author: Henni Rosaini
ABSTRACT
Gambir has effectiveness as an antimicrobial and antioxidant. Compounds that act as antimicrobials and antioxidants in gambier are catechins. The purposes of this study are 1) determine the capability of catechins formulated in the form of peel off gel mask preparations 2) determine the PVP K-30 concentrations effect on the physical properties of catechin peel off gel masks from gambir. The peel off gel mask formula was designed into four formulas with the same active substance concentration of 6%, except for F0 without the active substance as a control. The variations of PVP K-30 concentrations added were 3%, 4% and 5%. The function of PVP K-30, PVA 10%, propilenglycol 10%,nipagin 0.18 and nipasol 0.02 addition were as gelling agents, as film-forming, as humectant, as preservatives, respectively. While, distilled water and ethanol 70% were as solvents and essential citrus was as deodorizers. Based on the research results and the physical properties evaluation of peel off gel mask preparations shows that catechins can be formulated in the form of peel off gel masks. Also, the variations of PVP K-30concentration have an influence on the physical properties of peel off gel mask preparations. Concentration of PVP K-30 contained in the maxillary gel peel off preparation can reduce the color intensity and increase the pH and drying time. Different result was found in the spread power test. The increasing of PVP concentration K-30 can reduce the spread of the gel peel off catechin mask preparation from gambir.
Keywords: Formulation, peel-off gel mask, catechin, gambir, PVP K-30.
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