Original Research Article
Year: 2021 | Month: November | Volume: 8 | Issue: 11 | Pages: 10-16
DOI: https://doi.org/10.52403/ijrr.20211102
Correlation of Reticulocyte Hemoglobin Equivalent (Ret-He) Levels and Iron Deficiency Anemia in CKD Patients Treating Regular Hemodialysis
Husni Gunawan Hasibuan1, Syafrizal Nasution2, Radar Radius Tarigan2
1Department of Internal Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia
2Division of Nephrology and Hypertension, Department of Internal Medicine, Faculty of Medicine,
Universitas Sumatera Utara, Medan, Indonesia
Corresponding Author: Husni Gunawan Hasibuan
ABSTRACT
Background: Anemia appears in the early stages of CKD and its prevalence increases as kidney function declines. Ret-HE can be used to diagnose iron-deficiency anemia. Indonesia does not yet have appropriate research data on RET-He levels in CKD patients undergoing hemodialysis as a parameter to assess iron. Therefore, this study aims to examine the ability of RET-He as an alternative parameter to assess iron deficiency in hemodialysis patients.
Method: This research is a correlation analytic study with a cross-sectional design, carried out in February-May 2021 at the Hemodialysis Installation of H. Adam Malik Hospital. Blood sample collection and examination are carried out at the Clinical Pathology Laboratory. Primary and secondary data were collected from interviews, questionnaires, or patient medical records. The data will be analyzed by Pearson correlation test using SPSS software.
Results: A total of 41 samples consisted of 31 anemic patients and 10 anemic patients with normal RET-He levels. Demographic characteristics based on age group with an average of 47±13.28 years. The correlation of Ret-HE and TSAT levels in CKD patients undergoing hemodialysis shows a significance value of 0.000, so it can be concluded that there is a correlation between RET-HE and TSAT levels with a significance value of <0.05. According to the Pearson correlation number of 0.618 which is in the range of 0.61 to 0.80.
Conclusion: There is a positive correlation between Ret-HE levels and iron deficiency anemia in CKD patients undergoing regular hemodialysis.
Keywords: CKD, RET-HE, Hemodialysis.
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