Case Report
Year: 2020 | Month: July | Volume: 7 | Issue: 7 | Pages: 94-96
Acrokeratosis Verruciformis of Hopf: A Rare Case Report
N.T. Chaitanya
Post graduate, Department of Dermatology, Venereology and Leprosy, J J M Medical College, Rajiv Gandhi University of Health Sciences, Davanagere, Karnataka-577004, India,
ABSTRACT
Acrokeratosis verruciformis (AKV) of Hopf is a rare autosomal dominant genodermatosis characterised by multiple hyperkeratotic, skin-coloured, verrucous papules on hands and feet. We present a 4-year-old female with itchy lesions around the right ankle since the age of 3 months without any family history of AKV. Clinical investigation showed multiple hyperpigmented, hyperkeratotic grouped papules and histopathology showed hyperkeratosis, acanthosis, papillomatosis with church-spire like elevation of the epidermis without signs of dyskeratosis and mild lymphocytic infiltrate in the dermis. Treatment with 0.05% topical tretinoin showed improvement within two weeks.
Keywords: Histopathology, differential diagnosis, follow-up, genodermatosis, Tretinoin, treatment
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