Original Research Article
Year: 2020 | Month: February | Volume: 7 | Issue: 2 | Pages: 163-167
Relationship of Serum Retinol and Vitamin B12 to Essential Hypertension - An Observational Study in Eastern India
Subhramay Chatterjee1, Sandip Chakraborti2
1Associate Professor, Biochemistry Department, Murshidabad Medical College and Hospital, Berhampore, West Bengal, India
2Associate Professor, Biochemistry Department, NRS Medical College and Hospital, Kolkata, West Bengal, India
Corresponding Author: Sandip Chakraborti
ABSTRACT
Pathophysiology of essential hypertension has been linked to various factors including nutrition. 139 essential hypertension cases were divided into group 1 (67 younger cases, <50 years of age) and group 2 (72 older cases, more than 50 years of age. Serum retinol and vitamin B12 levels of the 139 cases and 127 nonhypertensive controls were assayed. There was no significant difference between the mean levels of serum vitamin B12levels of cases and controls, though the levels of serum vitamin B12were decreased in cases in comparison to controls. But, mean levels of serum retinol were significantly decreased in cases with respect to controls, and the decrease was more significant in older patients when compared to younger patients. Levels of serum retinol are decreased in essential hypertension and this decrease is more as age advances, but levels of serum vitamin B12 are unchanged in essential hypertension. Retinol may be used as a marker for essential hypertension, though further studies in this regard are required to validate the present observations.
Keywords: Essential hypertension, serum retinol, vitamin B12
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