Case Report
Year: 2020 | Month: November | Volume: 7 | Issue: 11 | Pages: 321-323
Collecting Duct Carcinoma; A Rare Renal Neoplasm – A Case Report
Debaditya Samanta1, Asim Kumar Manna2
1Post Graduate Trainee, 2Professor, Department of Pathology, Institute of Post Graduate Medical Education and Research, Kolkata.
Corresponding Author: Debaditya Samanta
ABSTRACT
Collecting duct carcinoma is a rare type of renal tumour, arising from the distal collecting duct epithelium in contrast to majority of the renal cell carcinoma which arises from the proximal tubular epithelium. It accounts for <1% of all the renal carcinomas. The prognosis of this disease is extremely poor due to its rapid progression with widespread metastases. We present a case of collecting duct carcinoma involving the left renal upper pole region of a 70 years old female presented with right flank pain that had persisted for 2 months. A computed tomography scan demonstrated a mass measuring 5x4 cm at upper pole of left kidney with pelvic-calyceal system involvement. Following that left radical nephrectomy was done. Histological examination demonstrated that a tumour mass composed of cuboidal to columnar cells in irregular duct like structure, nests, cords and occasional tubule-papillary arrangement. Immunohistochemical staining revealed that the tumour cells were positive for CK7 and High Molecular Weight Cytokeratin (HWMCK) and negative for CD10 and p63. Hence the diagnosis of collecting duct carcinoma was confirmed.
Keywords: Collecting duct carcinoma, renal neoplasm, renal tumour.
[PDF Full Text]