Original Research Article
Year: 2019 | Month: September | Volume: 6 | Issue: 9 | Pages: 214-219
A Study of 50 Cases of Cerebral Venous Sinus Thrombosis
Mugundhan Krishnan1, Murugapandian Nagarajan2
1Associate Professor in Neurology, Government Kilpauk Medical College, Chennai, India.
2Senior Assistant Professor in Neurology, Government Kilpauk Medical College, Chennai, India.
Corresponding Author: Murugapandian Nagarajan
ABSTRACT
Background: We undertook this study to analyze the demographic profile, frequency of different clinical features, risk factors, and prognostic outcome in patients suffering from cerebral venous thrombosis in our institution.
Methods: We performed a retrospective descriptive-analytical study in which 50 patients with cerebral venous-sinus thrombosis, who referred to Department of Neurology, Government Kilpauk Medical College from January 2017 to March 2019, were included, and their demographic, etiologic(risk factors), clinical, radiological and prognostic characteristics were evaluated.
Results: Out of 50 patients, there were 11 males (22%) and 39 females (78%); age ranged from 14 years to 72 years; headache was the most common symptom in 48/50 (96%), followed by paresis 23/50 (46%), seizures 22/50 (44%), papilledema 19/50 (38 %), mental status disorder 15/50 (30%), and aphasia 9/50 (18%). In majority of the patients 26 (52%), Pregnancy or Puerperium was the risk factor. The most common sinus involved was superior sagittal sinus(n-32), followed by almost equal involvement of transverse and sigmoid sinuses(n-29).Poor prognostic factors at the time of admission were stupor or coma (P=0.001) and parenchymal with or without subarachnoid hemorrhage in first CT scan.
Conclusion: Sinus thrombosis remains a diagnostic challenge and a potentially disabling or lethal disease, but improved diagnosis by recent advances and treatment now result in an excellent outcome for most patients.
Key words: Cerebral Venous Sinus Thrombosis; Pregnancy and Puerperium; Superior Sagittal Sinus
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