Original Research Article
Year: 2019 | Month: September | Volume: 6 | Issue: 9 | Pages: 5-8
The Association between Vitamin D Deficiency and Dyslipidemia
Dr Suman Doddamani1, Dr Puneet Shetty2
1Assistant Professor, Department of Biochemistry, Sanjay Gandhi Institute of Trauma and Orthopaedics, Bengaluru - 11
2Senior Resident, Department of Orthopaedics, Sanjay Gandhi Institute of Trauma and Orthopaedics, Bengaluru - 11
Corresponding Author: Dr Puneet Shetty
ABSTRACT
Background: Vitamin D deficiency is one of the commonest disorder found in all age groups. Some studies suggest that vitamin D deficiency may have an influence on lipid parameters. Dyslipidemia is an independent risk factor in development of cardiovascular diseases.
Aims and objectives: The aim of our study was to find the association between Vitamin D deficiency and dyslipidemia.
Materials and Methods: The study group comprised of 50 patients with Vitamin D deficiency in the age group of 20-60 years. 50 age and sex matched healthy participants comprised the control group. The blood samples of all the participants were used for measuring vitamin D levels and Lipid profile. HDL cholesterol level and total cholesterol was measured by Cholesterol Oxidase Peroxidase method. Triacylglycerol estimation was done by Glycerol 3-Phosphate Oxidase – Peroxidase method. VLDL and LDL cholesterol were calculated by formula given in Tietz textbook.
Results: Total cholesterol and LDL were significantly elevated in participants with vitamin D deficiency compared to the control participants. Total cholesterol, Triglyceride and VLDL have significant negative correlation with vitamin D deficient patients, whereas there was no significant correlation with the lipid parameters in control participants.
Conclusion: The present study showed increased levels of trigycerides, total cholesterol, VLDL, LDL and decreased HDL in vitamin D deficient patients compared to the control participants. Thus patients with vitamin D deficiency should be evaluated for abnormalities in lipid profile.
Key words: Vitamin D, Dyslipidemia, Lipid profile, Diabetes Mellitus
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