Original Research Article
Year: 2019 | Month: August | Volume: 6 | Issue: 8 | Pages: 393-398
Study on Phytochemical Constituents and Evaluation of Radical Scavenging Activity of Myanmar Traditional Medicinal Plant Stemona curtisii Hook f.
Aye Mon Thida Nyo1, Arnt Win2, Sabai Phyu3
1Associate Professor, Department of Chemistry, University of Mandalay, Myanmar
2Associate Professor, Department of Chemistry, Kyaukse University, Myanmar
3Assistant Lecturer, Department of Chemistry, Yadanar Pon University, Myanmar
Corresponding Author: Aye Mon Thida Nyo
ABSTRACT
In this study, rhizomes of Stemona curtisii Hook f., family Stemonaceae were selected for chemical investigations. The rhizomes of S. curtisii Hook f., Myanmar named Tha-myar were collected from Kalay Township, Chin State, Northern-west of Myanmar. The constituents of phytochemical compounds from selected plant were isolated and their structures were elucidated. Two alkaloid compounds, stemofoline (1), isostemofoline (2) and other three compounds (3-5) were isolated from ethyl acetate portion of S. curtisii Hook f. by Thin Layer and Column Chromatography methods at Meijo University, Nagoya, in Japan. The structures of these compounds were elucidated by 1D and 2D NMR spectroscopy and mass spectrometry. The radical scavenging activity of ethyl acetate extract of rhizome of S. curtisii Hook f. was evaluated by DPPH assay method.
Key words: Stemona curtisii Hook f., Stemonaceae, 1D and 2D NMR spectroscopy, DPPH Assay method, radical scavenging activity.
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