Original Research Article
Year: 2019 | Month: July | Volume: 6 | Issue: 7 | Pages: 152-156
Association of Vitamin D and HbA1c in Type II Diabetes Mellitus Patients
Dr Ayesha Juhi
Associate Professor, Department of Physiology, Apollo Institute of Medical Science and Research, HyderabadABSTRACT
Diabetes mellitus being a metabolic disorder is characterized by chronic hyperglycemia due to impaired insulin secretion, peripheral insulin resistance, or both. Vitamin D serves several hormonal functions on various cell types that express vitamin D receptors (VDRs) on them. Vitamin D deficiency may play a key role in the development of impaired glucose tolerance, type II diabetes mellitus and metabolic syndrome. The main aim of this study is to see the association of vitamin D and HbA1c levels in diabetes mellitus type II patients. Material and methods: This is a cross sectional study, conducted on 63 Diabetes mellitus type II patients in the age group of 30-70 years. HbA1c levels were correlated with their serum 25(OH) VITAMIN D3 levels. Pearson correlation statistical test was chosen to see the relation between HbA1c levels and serum25 (OH) VITAMIN D3 levels. Results: Pearson’s correlation r value obtained was r= -0.3 which shows an inverse relationship between the two variables. P value obtained for correlation was 0.013 which showed a significant negative correlation. Conclusion: By the results obtained in the study, vitamin D levels were deficient than optimal levels among diabetic type II patients .These inadequate levels of vitamin D among them could one be the cause for their hyperglycemic state. And also the poor gylcemic control in them could also lead to deficient Vitamin D levels among them. Based on these results it would be physiologically correct to recommend vitamin D supplementation to improve glucose control in type 2 diabetes mellitus patients.
Key words: 25(OH) Vitamin D3, HbA1c (glycosylated hemoglobin) , Diabetes mellitus type II
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