IJRR

International Journal of Research and Review

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Original Research Article

Year: 2019 | Month: December | Volume: 6 | Issue: 12 | Pages: 449-455

To Evaluate Efficiency of Curcumin and Honey in Patients with Recurrent Aphthous Stomatitis: A Randomized Clinical Controlled Trial

Rucha Pandharipande1, Rakhi Chandak2, Ramhari Sathawane3, Ashish Lanjekar2, Romita Gaikwad4, Vaishali Khandelwal1, Krishna Kurawar1

1Post Graduate Student, 2Reader, 3Professor & HOD, 4Senior Lecturer,
Department of Oral Medicine and Radiology, Swargiya Dadasaheb Kalmegh Smruti Dental College and Hospital, Hingna Nagpur.

Corresponding Author: Rucha Pandharipande

ABSTRACT

Introduction: Recurrent aphthous stomatitis (RAS) is one of the most common painful oral mucosal conditions seen among patients. Natural products have been used for several years in traditional medicine. Nowadays there are some natural remedies that are being explored for the treatment of aphthae. Herbal medicine will relieve pain, reduce inflammation and prevent infection in aphthous ulcers. Therefore, the present study was conducted to evaluate the efficiency of herbal remedies in the treatment of recurrent aphthous stomatitis.
Materials & Methods: The study population consisting of 105 patients having recurrent minor aphthous ulcer were selected from the outpatients of Department of Oral Medicine and Radiology, SDKS Dental College and Hospital. Patients were divided randomly into three groups ie Curcumin, Honey, Orabase group, each group consisting of 35 patients. Patients were evaluated on size, VAS score, erythema and exudate & were recalled on 3rd and 7th day of the treatment.
Results: The present study showed that all the three groups i.e Curcumin, Honey and Orabase were effective in improving the size, VAS score as well as the erythema and exudation levels. On comparison between the groups, Curcumin group showed statistically significant result as compared to Honey and Orabase group in improving the size, VAS score as well as the erythema and exudation levels. Therefore, Curcumin was the most effective in all the three groups.
Conclusion: Both Curcumin and Honey can be used as an alternative treatment modality in the management of RAS with Curcumin being slightly more effective than Honey.

Key words: Curcumin, Honey, Aphthous ulcer, RAS.

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