IJRR

International Journal of Research and Review

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Review Article

Year: 2019 | Month: November | Volume: 6 | Issue: 11 | Pages: 399-407

Overview of the Cardiovascular Risk in Rheumatoid Arthritis

Vidhya PV, Cindy J, Sambathkumar R

Department of Pharmacy Practice, J.K.K. Nattraja College of Pharmacy, Kumarapalayam – 638183, Tamil Nadu, India

Corresponding Author: Cindy J

ABSTRACT

Rheumatoid arthritis (RA) is a chronic inflammatory joint disorder that impacts nearly 1% of the general population and ranks among the top 15% of illnesses that cause significant disabilities worldwide. RA shares atherosclerosis with certain pathological characteristics, genetic predisposition and risk factors. Patients with rheumatoid arthritis (RA) have been shown to have increased cardiovascular morbidity and mortality, including the danger of sudden cardiac death (SCD). Inflammation plays a key role in both illnesses of pathophysiology. Abnormalities in autonomic markers such as variation in heart rate and parameters of ventricular repolarization, such as QTc interval and QT dispersion, were correlated with sudden death in RA patients. Based on latest clinical research, this paper will review briefly the cardiovascular complications of rheumatoid arthritis.

Key words: Rheumatoid arthritis, Cardiovascular risks, Rheumatoid arthritis, Extra articular complications.

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