Year: 2026 | Month: May | Volume: 13 | Issue: 5 | Pages: 687-692
DOI: https://doi.org/10.52403/ijrr.20260566
GCMS Profiling of Bioactive Phytocompounds in Irumal Maathirai: A Traditional Siddha Polyherbo-Mineral Formulation for Cough and Respiratory Ailments
Dr Sathya Priya R1, Dr G Chenthamarai Selvi2
1PG Scholar, Department of Nanju Maruthuvam, Government Siddha Medical College and Hospital, Palayamkottai, Tamil Nadu, India.
2Assistant Professor, Department of Nanju Maruthuvam, Government Siddha Medical College and Hospital, Palayamkottai, Tamil Nadu, India.
Corresponding Author: Dr Sathya Priya R
ABSTRACT
Irumal Maathirai (IM) is a classical Siddha polyherbal-mineral formulation used for the management of Irumal (Cough) and various other respiratory ailments.
Objective: The objective of this study is to characterize the volatile and semi-volatile bioactive compounds present in Irumal maathirai by Gas Chromatography and Mass Spectrometry method.
Methods: An ethanolic extract of Irumal maathirai was subjected to GC-MS profiling, with compound identification achieved by cross-referencing mass spectra against the NIST library database.
Results: Several distinct peaks were revealed in The Total Ion Chromatogram (TIC). Predominant compounds identified include 10-Octadecenoic acid, methyl ester, Pentadecanoic acid, 13-methyl-, methyl ester, Pyrimidine-5-carboxylic acid, 1,4-dihydro-4-(2-furyl)-1,6-dimethyl-2-methylthio-, ethyl ester, 2-Isopropenyl-4,4,7a-trimethyl-2,4,5,6,7,7a-hexahydrobenzofuran-6-ol.
Conclusion: The identified compounds possess established pharmacological properties, including anti-inflammatory, antimicrobial, bronchodilator and anti-oxidant effects, which provides a scientific rationale for the traditional therapeutic efficacy of Irumal Maathirai in treating various respiratory ailments, supporting its potential as a standardized phytopharmaceutical.
Keywords: Irumal maathirai, GC-MS, cough, anti-inflammatory, antimicrobial, bronchodilator, siddha medicine.
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