IJRR

International Journal of Research and Review

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Year: 2026 | Month: May | Volume: 13 | Issue: 5 | Pages: 560-564

DOI: https://doi.org/10.52403/ijrr.20260551

Phytochemical Profiling of Thumattikai Mezhugu - A Siddha Formulation

Dr. Maniprabha G1, Dr. S Balamani2

1PG 3rd year scholar, Department of Nanju Maruthuvam, Government Siddha Medical College, Palayamkottai.
2Assistant Professor, Department of Nanju Maruthuvam, Government Siddha Medical College & Hospital, Palayamkottai.

Corresponding Author: Dr. Maniprabha G

ABSTRACT

BACKGROUND: Standardization of the Siddha polyherbal formulation Thumatti Mezhugu, is crucial to ensure its authenticity, quality, and effectiveness. It is essential to validate their potency and efficacy for global acceptance, especially as public interest in traditional medicine continues to grow. Thumatti Mezhugu, a traditional Siddha formulation used for PCOS, amenorrhea, and dysmenorrhea, was evaluated through qualitative phytochemical analysis using standard methods to assess its therapeutic potential. Phytochemicals are valuable medicinal agents, and there is an urgent need to develop new drugs with novel structures and mechanisms to address the challenges posed by emerging diseases.
Methods: Thumatti mezhugu has been standardized as per siddha pharmacopoeia standard protocol guidelines and prepared Mezhugu formulation composed of seven ingredients such as Citrullus collocynthis, Ferula asafoetida, Borax, Sodium chloride impura, Piper cubeba, Nigella sativa, Picrorhiza kurroa.
Results: Thumatti mezhugu was found to contain alkaloids, phenols, flavonoids, steroids, glycosides, tannins, and diterpenes. The Siddha medicine Thumatti mezhugu contains various phytochemical compounds that can be potential drugs for human use. The analysis further identified absence of Saponins, Proteins, Anthocyanins and Betacyanins, with further heavy metal testing recommended for standardization.

Keywords: Thumattikai mezhugu, Dysmenorrhoea, PCOS, Phytoconstituents, alkaloids

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