Research Paper
Year: 2023 | Month: August | Volume: 10 | Issue: 8 | Pages: 903-912
DOI: https://doi.org/10.52403/ijrr.202308115
Biochemical, Physicochemical, Preliminary Phytochemical Evaluation of Kadukkai Poo Choornam
Rishipriya. C. R1, A. Manoharan2, P. Sathish Kumar3
1PG Scholar, Department of Pothu Maruthuvam, Government Siddha Medical College and Hospital, Palayamkottai, Tirunelveli - 627002, Tamilnadu, India
2Professor and HOD, Department of Pothu Maruthuvam, Government Siddha Medical College and Hospital, Palayamkottai, Tirunelveli – 627002, Tamilnadu, India
3Lecturer, Department of Pothu Maruthuvam Government Siddha Medicine College and Hospital, Palayamkottai, Tirunelveli -627002, Tamilnadu, India
Corresponding Author: Rishipriya. C. R
ABSTRACT
Background: Kadukkai Poo Choornam is a poly herbal formulation in Siddha system of medicine mainly indicated for the management of bleeding hemorrhoids. According to Siddha system, medicine is a substance that helps to alleviate or eradicate the disease, gives strength to the body and normalizes the functions of the body. In Siddha system mainly the herbal formulations gained worldwide attention due to its long-term benefits in terms of overall wellness with lesser side effects. But there is striving for global acceptance due to lack of scientific validation and documentation. To overcome these limitations and ensure the quality, safety and therapeutic efficacy modern methods can be incorporated.
Aim and Objective: The aim of this study is to evaluate the biochemical, phytochemical and physico chemical properties of kadukkai poo choornam.
Methodology: The extraction of the drug was done by soxhelt method and phytochemical screening was done for the presence of alkaloids, glycosides, phenols, terpenoids carbohydrates, quinones, steroids, Saponins and proteins. Biochemical analysis was carried out to detect the presence of sulphate, chloride, carbonate, starch, ferrous iron, tannic acid, phosphate, zinc, reducing sugar and albumin. The Physicochemical analysis also carried out using standard procedures.
Results: The phytochemical screening revealed the presence of alkaloids, glycosides, phenols, terpenoids, carbohydrates, tannins and quinones. The developed qualitative densitometric HPTLC fingerprint can be used as an identifying biological marker for the drug extracts. In biochemical analysis the presence of Sulphate, chloride, reducing sugar, tannins and unsaturated compound. Physicochemical analysis revealed the values of total ash, acid insoluble ash, water soluble ash, sulphated ash, pH, volatile oil, foaming index and swelling index.
Conclusion: This study is an attempt to validate the therapeutic efficacy of kadukkai poo choornam for the management of hemorrhoids. And the above study can be used in further clinical studies and drug standardization.
Keywords: Kadukkai poo choornam, biochemical analysis, physicochemical, phytochemical screening, Polyherbal formulation, hemorrhoids
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