IJRR

International Journal of Research and Review

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Review Article

Year: 2023 | Month: July | Volume: 10 | Issue: 7 | Pages: 660-670

DOI: https://doi.org/10.52403/ijrr.20230778

Paraneoplastic Syndromes in Small Cell Lung Cancer: A Narrative Review

Archana Rajan1, Abhisek Sahoo2

1Department of Medicine, 2Department of Physiology,
All India Institute of Medical Sciences, New Delhi, India

Corresponding Author: Archana Rajan

ABSTRACT

Paraneoplastic syndromes are commonly associated with lung cancer, particularly small-cell lung cancer. These syndromes often occur before the cancer is diagnosed or in the early stages of the disease. However, they can also occur at the time of metastasis. Through this article, we want to focus on the epidemiology, pathophysiology, symptoms, and current treatment approaches for the most frequent paraneoplastic syndromes seen in patients with small-cell lung cancer. Recent advancements have improved our understanding of these syndromes and provided better diagnostic and therapeutic options. Being aware of paraneoplastic syndromes in small-cell lung cancer can lead to earlier detection and diagnosis, potentially improving the overall prognosis and survival rates for patients. Further studies are needed to investigate effective strategies in patients with paraneoplastic neurological disorders.

Keywords: Paraneoplastic syndrome, small cell lung cancer, hypercalcemia

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