Year: 2023 | Month: October | Volume: 10 | Issue: 10 | Pages: 291-298
DOI: https://doi.org/10.52403/ijrr.20231036
The Association of Psoriasis and Multiple Sclerosis: A Narrative Review
Nadyah Abdullah Owaidhah1, Mohammed Abdullah Alahmadi2, Shuruq Talea Asiri3, Shahad Fayez Albalawi4, Hadeel Abdulrahman Aljoufi4
1Department of Family and Community Medicine, Assistant Professor Family Medicine, Taibah University, Al-Madinah al-Munawwarah, Saudi Arabia.
2Department of Medicine and Surgery, Taibah University, Al-Madinah al-Munawwarah, Saudi Arabia.
3Department of Medicine and Surgery, Najran University, Najran City, Saudi Arabia.
4Department of Medicine and Surgery, Jouf University, Al-Jouf City, Saudi Arabia.
Corresponding Author: Mohammed Abdullah Alahmadi
ABSTRACT
Multiple sclerosis (MS) and psoriasis (PsO) are inflammatory diseases that share genetic risk variations and inflammatory mechanisms. The precise connection between PsO and MS has been the subject of earlier investigations, but it is still unclear because there is little conflicting data to support such a connection. There are several risk factors in common between PsO and MS, and disease-modifying treatments are powerful treatments for both PsO and MS, indicating a shared pathophysiology. In this narrative review, we have revised the causes, pathophysiology, diagnosis, and treatment of each condition. Also, we summaries the current research on any potential connections between PsO and MS. We come to the conclusion that more research is required to determine whether PsO and MS may have a meaningful association. In order to enable fast referral to a neurologist, if necessary, physicians may decide that it is prudent to assess individuals with PsO for MS.
Keywords: Psoriasis, Multiple sclerosis, Autoimmune disease, Co-morbid patients.
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