Original Research Article
Year: 2016 | Month: June | Volume: 3 | Issue: 6 | Pages: 16-19
Hyperprolactinemia and Hypothyroidism in Population of East Medinipur, West Bengal: A Hospital Based Study
Ajay Kumar Das1, Naved Ahmad2, Akash Gupta3
1Associate Professor, Department of Biochemistry, ICARE institute of medical sciences and research, East Medinipur, W.B. India.2Demonstrator, Department of Biochemistry, FH Medical College, Tundla, U.P.
3Assistant Professor, Department of Biochemistry, Subharti Medical College, Meerut U.P.
Corresponding Author: Akash Gupta
ABSTRACT
Introduction: Hyperprolactinemia is one of the most rampant endocrine disorders in hypothalamic- pituitary axis. Hypothyroidism refers to state that results in a deficiency of thyroid hormones, including hypothalamic or pituitary disease and generalized tissue resistant to thyroid hormone. Thyroid releasing hormone can causes rise in serum prolactin levels in patients of primary hypothyroidism.
Methods: A total of 170 patients presenting to endocrinology clinic for various thyroid related problems were selected. Serum T3, T4, TSH and Prolactin were analyzed by using Bensphera enzyme linked immunosorbent assay kit from Avantor, on Lablife ER2007 elisa reader from Diagnova India.
Results: Prolactin level is high in the subclinical hypothyroid patients and hypothyroid patients as compared to euthyroid patients.
Conclusion: Hyperprolactinemia was an important feature in patients with newly diagnosed hypothyroid and subclinical hypothyroid patients.